The intra and intermolecular interaction study is an interesting research topic in molecular science. The formation of a solute-solvent complex structure in mixture liquids could affect the chemical equilibrium, reaction rate, and production yield. Thus, acquiring accurate knowledge of molecular structure has been the subject of current research in various fields of chemical physics and biology. The material-dependent dielectric and thermodynamic studies of binary liquid mixtures could provide the dynamic and structural characteristics of molecular aggregation patterns. Therefore, we have adapted the dielectric relaxation spectroscopy method to investigate the molecular network formation, polarization strength, reorientation dynamics, and physic-chemical properties of the mixture solution. The ultimate aim of the present work is to study the intermolecular interaction and dielectric relaxation of binary mixtures of various structures of nitro molecules with different positions of Hydroxyl functional group in the molecules of alcohol at certain temperature ranges.